The 2025/26 Premier League fixture list has been announced, and Arsenal fans will be looking for several key clashes.
After finishing second three seasons in a row, Mikel Arteta will be hungrier than ever to deliver the Premier League title to N5.
Arsenal haven’t won the league since Arsene Wenger’s Invincibles went the entire campaign unbeaten in 2003/04, but signs of improvement are certainly there.
Following years of being schooled by the Premier League’s ‘big six’, Arteta hasn’t seen his team lose to a team within that category in over two years.
Though the Premier League table over recent years will tell you otherwise, the big six are categorised as Manchester City, Liverpool, Chelsea, Manchester United, Tottenham Hotspur, and, of course, Arsenal.
The big six clashes, including the North London Derby, are what fans will be eyeing from the 2025/26 schedule, so with that said, here are all of the key dates supporters need to know.

Arsenal vs Tottenham
Everyone’s eyes will immediately look for the dates of Arsenal’s meeting with Tottenham, both home and away.
- Arsenal vs Tottenham Hotspur – Emirates Stadium – 22nd November – Gameweek 12
- Tottenham Hotspur vs Arsenal – Tottenham Hotspur Stadium – 21st February – Gameweek 27
- READ MORE: What is the North London Derby? Everything you need to know about the Arsenal and Tottenham rivalry

Arsenal vs Manchester United
Wenger and Sir Alex Ferguson took Arsenal’s rivalry with Manchester United to new heights, making it a clash that’s always highly contested.
It’s been announced that Arsenal will face Man United on matchday one, kicking the campaign off with a blockbuster.
- Arsenal vs Manchester United – Emirates Stadium – 24th January – Gameweek 23
- Manchester United vs Arsenal – Old Trafford – 17th August – Gameweek One

Arsenal vs Liverpool
Liverpool and Arsenal were title rivals last season, and in 2025/26, one thing the Gunners will be desperate to do is break their curse at Anfield.
- Arsenal vs Liverpool – Emirates Stadium – 7th January – Gameweek 21
- Liverpool vs Arsenal – Anfield – August 30th – Gameweek three

Arsenal vs Manchester City
Arsenal’s clashes with Manchester City were dramatic last term, with a last-gasp 2-2 draw and a 5-1 demolition at the Emirates taking place when Arteta and Pep Guardiola reunited.
- Arsenal vs Manchester City – Emirates Stadium – 20th September – Gameweek five
- Manchester City vs Arsenal – Etihad Stadium – 18th April – Gameweek 33

Arsenal vs Chelsea
It’s not just the North London Derby that fans are eager to see, as Arsenal have key clashes all over the capital, including Chelsea.
- Arsenal vs Chelsea – Emirates Stadium – 28th February – Gameweek 28
- Chelsea vs Arsenal – Stamford Bridge – 29th November – Gameweek 13

Arsenal vs West Ham United
Declan Rice has become the poster boy of the Gunners’ meetings with West Ham since signing in 2023, and he’s not a sight that the Hammers will want to see too often.
- Arsenal vs West Ham United – Emirates Stadium – 4th October – Gameweek seven
- West Ham United vs Arsenal – London Stadium – 9th May – Gameweek 36

Arsenal vs Crystal Palace
The 2025 FA Cup winners aren’t a side to be overlooked in any regard, as Arsenal know, having lost to Oliver Glasner’s side last season.
- Arsenal vs Crystal Palace – Emirates Stadium – 25th October – Gameweek nine
- Crystal Palace vs Arsenal – Selhurst Park – 24th May – Gameweek 38

Arsenal vs Brentford
Thomas Frank was an admirer of Arsenal at Brentford, but his opinion will surely be swayed after leaving the Bees to join Spurs.
- Arsenal vs Brentford – Emirates Stadium – 3rd December – Gameweek 14
- Brentford vs Arsenal – Gtech Community Stadium – 11th February – Gameweek 26

Arsenal vs Fulham
Arsenal and Fulham have shared several players in recent years, making this London derby a reunion of sorts.
- Arsenal vs Fulham – Emirates Stadium – 2nd May – Gameweek 35
- Fulham vs Arsenal – Craven Cottage – 18th October – Gameweek eight
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